Sonoran Desert toad venom

Sonoran Desert toad venom for sale online delivery, (Incilius alvarius, also known as the Colorado River toad or bufo toad) releases a poison through its skin that contains a psychedelic compound with therapeutic potential. The 5-MeO-DMT molecule, which is secreted naturally by the parotid glands of this amphibian, has hallucinogenic properties: when consumed, it causes temporary distortions of vision, sound and time perception. But the trips triggered by this compound may also impact mental health, and the scientific community is investigating its properties to treat depression and other mental disorders.

A study published on Wednesday in the journal Nature provides further insight into this type of psychedelic and its medicinal possibilities. Researchers from the Icahn Faculty at Mount Sinai in New York mapped the molecular bases of 5-MeO-DMT in the brain and analyzed how it interacts with the same serotonin receptor that is used in other antidepressants. The researchers believe the study provides “crucial information” to facilitate the development of new neuropsychiatric therapies.

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Amid the growing interest in psychedelic medicine, many scientists are looking at the therapeutic potential of 5-MeO-DMT. It is already being tested in humans, in a handful of trials for treatment-resistant depression. But the mechanism of action — i.e. how the compound impacts the brain — remains unclear. Scientists are paying special attention to how it and other psychedelics interact with brain receptors that activate a key neurotransmitter for regulating mood: serotonin.

This chemical substance serves as a communication route for neurons, allowing them to send messages to each other. It also helps regulate various functions, such as mood, digestion, temperature, sleep and sexual function. Low concentration of serotonin is associated with the development of depression and other mental disorders. Some conventional antidepressants, such as Prozac, try to raise serotonin levels.

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Daniel Wacker, author of the study published in Nature, admits that what they know about the effects of 5-MeO-DMT, “comes from anecdotal reports”: “The psychedelic induces altered states of consciousness, which are often described as trips and cannot be equated to a high like that produced by cannabis. Trips involve […] hallucinations, but also so-called subjective effects that can range from pleasant mystical experiences and feelings of unity to negative experiences including fear, paranoia and vomiting.

5-MeO-DMT in particular has been associated with ego dissolution, that is, feelings of oneness with the universe, which could contribute substantially to the sustained antidepressant effects of psychedelics. However, this has not yet been demonstrated so far, and other studies, including ours, suggest that other mechanisms could also contribute to the antidepressant effects of 5-MeO-DMT2.”